Characteristic attributes in cancer microarrays
نویسندگان
چکیده
منابع مشابه
Characteristic attributes in cancer microarrays
Rapid advances in genome sequencing and gene expression microarray technologies are providing unprecedented opportunities to identify specific genes involved in complex biological processes, such as development, signal transduction, and disease. The vast amount of data generated by these technologies has presented new challenges in bioinformatics. To help organize and interpret microarray data,...
متن کاملCGH microarrays and cancer.
Genetic alterations are a key feature of cancer cells and typically target biological processes and pathways that contribute to cancer pathogenesis. Array-based comparative genomic hybridization (aCGH) has provided a wealth of new information on copy number changes in cancer on a genome-wide level and aCGH data have also been utilized in cancer classification. More importantly, aCGH analyses ha...
متن کاملExpression profiling in cancer using cDNA microarrays.
Currently there are over 1,000,000 human expressed sequence tag (EST) sequences available on the public database, representing perhaps 50-90% of all human genes. The cDNA microarray technique is a recently developed tool that exploits this wealth of information for the analysis of gene expression. In this method, DNA probes representing cDNA clones are arrayed onto a glass slide and interrogate...
متن کاملApplication Note, Microarrays in Cancer Research
An important goal in cancer research is to identify significant genomic alterations responsible for the emergence and progression of disease. It is now possible, with Affymetrix brand products, to perform extensive analysis of tumor genomes, including wholegenome chromosomal copy number analysis, systematic gene resequencing, and RNA expression analysis. This application note is to review recen...
متن کاملUsing Microarrays Cancer-Linked DNA Hypomethylation in Gastric Cancer
Although hypomethylation was the originally identified epigenetic change in cancer, it was overlooked for many years in preference to hypermethylation. Recently, gene activation by cancer-linked hypomethylation has been rediscovered. However, in gastric cancer, genome-wide screening of the activated genes has not been found. By using microarrays, we identified 1,383 gene candidates reactivated ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Biomedical Informatics
سال: 2002
ISSN: 1532-0464
DOI: 10.1016/s1532-0464(02)00504-x